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Chris T. Middleton
Publications
publications
22.
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
Andisheh Abedini, Annette Plesner, Ping Cao, Zachary Ridgway, Jinghua Zhang, Ling-Hsien Tu, Chris T Middleton, Brian Chao, Daniel J Sartori, Fanling Meng, Hui Wang, Amy G Wong, Martin T Zanni, C Bruce Verchere, Daniel P Raleigh, Ann Marie Schmidt
eLife
2016
10.7554/eLife.12977
21.
Fully absorptive 3D IR spectroscopy using a dual mid-infrared pulse shaper
Sudipta S. Mukherjee, David R. Skoff, Chris T. Middleton and Martin T. Zanni
Journal of Chemical Physics
2013
139
144205
20.
Simplified and economical 2D IR spectrometer design using a dual acousto-optic modulator
David R. Skoff, Jennifer E. Laaser, Sudipta S. Mukherjee, Chris T. Middleton & Martin T. Zanni
Chemical Physics
2012
422
8
19.
Base-Stacking Disorder and Excited-State Dynamics in Single-Stranded Adenine Homo-oligonucleotides
Charlene Su, Chris T. Middleton, & Bern Kohler
Journal of Physical Chemistry B
2012
116
10266
18.
Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor
Chris T. Middleton, Peter Marek, Ping Cao, Chi-cheng Chiu, Sadanand Singh, Ann Marie Woys, Juan J. de Pablo, Daniel P. Raleigh & Martin T. Zanni
Nature Chemistry
2012
4
355-360
17.
2DIR Spectroscopy of Human Amylin Fibrils Reflects Stable β-Sheet Structure
Lu Wang, Chris T. Middleton, Sadanand Singh, Allam S. Reddy, Ann M. Woys, David B. Strasfeld, Peter Marek, Daniel P. Raleigh, Juan J. de Pablo, Martin T. Zanni, James L. Skinner
Journal of the American Chemical Society
2011
133
16062-16071
16.
Utilizing Lifetimes to Suppress Random Coil Features in 2D IR Spectra of Peptides
Chris T. Middleton, Lauren E. Buchanan, Emily B. Dunkelberger, Martin T. Zanni
Journal of Physical Chemistry Letters
2011
2
2357-2361
15.
Development and Validation of Transferable Amide I Vibrational Frequency Maps for Peptides
Lu Wang, Chris T. Middleton, Martin T. Zanni, James L. Skinner
Journal of Physical Chemistry B
2011
115
3713-3724
14.
Residue-specific structural kinetics of proteins through the union of isotope labeling, mid-IR pulse shaping, and coherent 2D IR spectroscopy
Chris T. Middleton, Ann Marie Woys, Sudipta S. Mukherjee, Martin T. Zanni
Methods
2010
50
12-22
13.
The Sulfated Triphenyl Methane Derivative Acid Fuchsin is a Potent Inhibitor of Amyloid Formation by Human Islet Amyloid Polypeptide and Protects against the Toxic Effects of Amyloid Formation
Fanling Meng, Andisheh Abedini, Annette Plesner, Chris T. Middleton, Kathryn J. Potter, Martin T. Zanni, C. Bruce Verchere, Daniel P. Raleigh
Journal of Molecular Biology
2010
400
555-566
12.
Mode selectivity with polarization shaping in the mid-IR
David B. Strasfeld, Chris T. Middleton, Martin T. Zanni
New Journal of Physics
2009
11
105046
11.
Polarization shaping in the mid-IR and polarization-based balanced heterodyne detection with application to 2D IR spectroscopy
Chris T. Middleton, David B. Strasfeld, Martin T. Zanni
Optics Express
2009
17
14526-14533
10.
DNA Excited-State Dynamics: From Single Bases to the Double Helix
Chris T. Middleton, Kimberly de La Harpe, Charlene Su, Yu Kay Law, Carlos E. Crespo-Hernández, Bern Kohler
Annual Review of Physical Chemistry
2009
60
217-239
9.
Time-resolved infrared spectroscopy of the lowest triplet state of thymine and thymidine
Patrick M. Hare, Chris T. Middleton, Kristin I. Mertel, John M. Herbert, Bern Kohler
Chemical Physics
2008
347
383-392
8.
Solvent and Solvent Isotope Effects on the Vibrational Cooling Dynamics of a DNA Base Derivative
Chris T. Middleton, Boiko Cohen, Bern Kohler
Journal of Physical Chemistry A
2007
111
10460-10467
7.
Solution Phase Isomerization of Vibrationally Excited Singlet Nitrenes to Vibrationally Excited 1,2-Didehydroazepine
Gotard T. Burdzinski, Chris T. Middleton, Terry L. Gustafson, Matthew S. Platz
Journal of the American Chemical Society
2006
128
14804-14805
6.
The Crystalline Enol of 1,3-Cyclohexanedione and Its Complex with Benzene: Vibrational Spectra, Simulation of Structure and Dynamics and Evidence for Cooperative Hydrogen Bonding
Bruce S. Hudson, Dale A. Braden, Damian G. Allis, Tim Jenkins, Sergey Baranov, Chris Middleton, Robert Withnall, Craig M. Brown
Journal of Physical Chemistry A
2004
108
7356-7363
5.
Conformation and Orientation of the Retinyl Chromophore in Rhodopsin: A Critical Evaluation of Recent NMR Data on the Basis of Theoretical Calculations Results in a Minimum Energy Structure Consistent with All Experimental Data
Deepak Singh, Bruce S. Hudson, Chris Middleton, Robert R. Birge
Biochemistry
2001
40
4201-4204
4.
The inelastic incoherent neutron spectrum of crystalline oxamide
Bruce S. Hudson, John Tse, John Tse, Stewart Parker, Dale A. Braden, Chris Middleton
Chemical Physics
2000
261
249-260
3.
Bacteriochlorophyll and Carotenoid Excitonic Couplings in the LH2 System of Purple Bacteria
Sergei Tretiak, Chris Middleton, Vladimir Chernyak, Shaul Mukamel
Journal of Physical Chemistry
2000
104
9540-9553
2.
Exciton Hamiltonian for the Bacteriochlorophyll System in the LH2 Antenna Complex of Purple Bacteria
Sergei Tretiak, Chris Middleton, Vladimir Chernyak, Shaul Mukamel
Journal of Physical Chemistry B
2000
104
4519-4528
1.
Localized and Delocalized Electronic Excitations in Biological and Artificial Antenna Complexes
Sergei Tretiak, Chris Middleton, Vladimir Chernyak, Shaul Mukamel
Photoinduced Charge Transfer, Lewis Rothberg, Editor (World Scientific)
2000
116-127
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